Notable Publications

As part of our mission to connect researchers and promote thought across disciplines, we are posting relevant papers that may be of interest to SPINEWORK members.


Davis, O.C., Dickie, A.C., Mustapa, M.B. et al. Calretinin-expressing islet cells are a source of pre- and post-synaptic inhibition of non-peptidergic nociceptor input to the mouse spinal cord. Sci Rep 13, 11561 (2023).

Nikpasand M, Abbott RE, Kage CC, Singh S, Winkelstein BA, Barocas VH, Ellingson AM. Cervical facet capsular ligament mechanics: Estimations based on subject-specific anatomy and kinematics. JOR Spine. 2023 Jun 29;6(3):e1269. doi: 10.1002/jsp2.1269. PMID: 37780821; PMCID: PMC10540825.

Lijun Qi, Michael Iskols, David Shi, Pranav Reddy, Christopher Walker, Karina Lezgiyeva, Tiphaine Voisin, Mathias Pawlak, Vijay K. Kuchroo, Isaac Chiu, David D. Ginty, Nikhil Sharma. "A DRG genetic toolkit reveals molecular, morphological, and functional diversity of somatosensory neuron subtypes." bioRxiv 2023.04.22.537932; doi:

Annie Handler, Qiyu Zhang, Song Pang, Tri M. Nguyen, Michael Iskols, Michael Nolan-Tamariz, Stuart Cattel, Rebecca Plumb, Brianna Sanchez, Karyl Ashjian, Aria Shotland, Bartianna Brown, Madiha Kabeer, Josef Turecek, Genelle Rankin, Wangchu Xiang, Elisa C. Pavarino, Nusrat Africawala, Celine Santiago, Wei-Chung Allen Lee, C. Shan Xu, David D. Ginty. "Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch." bioRxiv 2023.03.17.533188; doi:

Shirvalkar, P., Prosky, J., Chin, G. et al. First-in-human prediction of chronic pain state using intracranial neural biomarkersNature Neuroscience 26, 1090–1099 (2023).

Suwaidi, Aisha Salim Al, Ibrahim M. Moustafa, Meeyoung Kim, Paul A. Oakley, and Deed E. Harrison. 2023. "A Comparison of Two Forward Head Posture Corrective Approaches in Elderly with Chronic Non-Specific Neck Pain: A Randomized Controlled Study" Journal of Clinical Medicine 12, no. 2: 542.


Wang JJH (2022) Theory and Applications in Biomedical Engineering after Discovering a New Human Organ “Interstitium”. J Clin Trials. S20:008.

Edward F. Owens, Lydia L. Dever, Ronald S. Hosek, Brent S. Russell, Stephanie Sullivan DC; Development of a mannequin lab for clinical training in a chiropractic program. J Chiropr Educ 1 October 2022; 36 (2): 147–152. doi:

Guohao Lin, Xiong Zhao, Weijie Wang, Tracey Wilkinson, The relationship between forward head posture, postural control and gait: A systematic review, Gait & Posture, Volume 98, 2022, Pages 316-329, ISSN 0966-6362,

Russell, B.S., Keller, M., Wynd, S.E., Hosek, R., Owens, E.F., and Hoiriis, K.T., "Angular kinematics of chiropractic supine manipulation: rotational measures and comparisons to doctor and and recipient perceptions," Journal of Manipulative and Physiological Therapeutics 45:497, 2022. DOI: 10.1016/j.jmpt.2022.12.002. 

Barbe, Mary F., Mamta Amin, Michele Y. Harris, Siva Tejaa Panibatla, Soroush Assari, Steven N. Popoff, and Geoffrey M. Bove. 2022. "Manual Therapy Facilitates Homeostatic Adaptation to Bone Microstructural Declines Induced by a Rat Model of Repetitive Forceful Task" International Journal of Molecular Sciences 23, no. 12: 6586.

Zhenghong Gao, Eric T. David, Tiffany W. Leong, Xiaoqing Li, Qi Cai, Juliet Mwirigi, Monica Giannotta, Elisabetta Dejana, John Wiggins, Sharada Krishnagiri, Robert M. Bachoo, Theodore J. Price, Zhengpeng Qin. 2022. Minimally invasive delivery of peptides to the spinal cord for behavior modulation bioRxiv 2022.05.20.492752; doi:

Bronfort, G., Maiers, M., Schulz, C. et al. Multidisciplinary integrative care versus chiropractic care for low back pain: a randomized clinical trial. Chiropr Man Therap 30, 10 (2022).

Funabashi M, Breen Ax, De Carvalho D, Pagé I, Nougarou F, Descarreaux M and Kawchuk GN (2022) Force Distribution Within Spinal Tissues During Posterior to Anterior Spinal Manipulative Therapy: A Secondary Analysis. Front. Integr. Neurosci. 15:809372. doi: 10.3389/fnint.2021.809372

Felipe C.K. Duarte, Martha Funabashi, David Starmer, Wania A. Partata, Daniel W.D. West, Dinesh A. Kumbhare, Stephen Injeyan, Effects of Distinct Force Magnitude of Spinal Manipulative Therapy on Blood Biomarkers of Inflammation: A Proof of Principle Study in Healthy Young Adults, Journal of Manipulative and Physiological Therapeutics, Volume 45, Issue 1, 2022, Pages 20-32, ISSN 0161-4754,


Breen A, De Carvalho D, Funabashi M, Kawchuk G, Pagé I, Wong AYL and Breen A (2021) A Reference Database of Standardised Continuous Lumbar Intervertebral Motion Analysis for Conducting Patient-Specific Comparisons. Front. Bioeng. Biotechnol. 9:745837. doi: 10.3389/fbioe.2021.745837

William Renthal, Alexander Chamessian, Michele Curatolo, Steve Davidson, Michael Burton, Sulayman Dib-Hajj, Patrick M. Dougherty, Allison D. Ebert, Robert W. Gereau, Andre Ghetti, Michael S. Gold, Gwendolyn Hoben, Daniela Maria Menichella, Philippe Mercier, Wilson Z. Ray, Daniela Salvemini, Rebecca P. Seal, Stephen Waxman, Clifford J. Woolf, Cheryl L. Stucky, Theodore J. Price, Human cells and networks of pain: Transforming pain target identification and therapeutic development, Neuron, Volume 109, Issue 9, 2021, Pages 1426-1429, ISSN 0896-6273,

van Dillen LR, Lanier VM, Steger-May K, et al. Effect of Motor Skill Training in Functional Activities vs Strength and Flexibility Exercise on Function in People With Chronic Low Back Pain: A Randomized Clinical Trial. JAMA Neurol. 2021;78(4):385–395. doi:10.1001/jamaneurol.2020.4821

Thornton JS, Caneiro JP, Hartvigsen J, et al Treating low back pain in athletes: a systematic review with meta-analysis British Journal of Sports Medicine 2021;55:656-662.


Menon, Rajiv G., Stephen F. Oswald, Preeti Raghavan, Ravinder R. Regatte, and Antonio Stecco. 2020. "T1ρ-Mapping for Musculoskeletal Pain Diagnosis: Case Series of Variation of Water Bound Glycosaminoglycans Quantification before and after Fascial Manipulation® in Subjects with Elbow Pain" International Journal of Environmental Research and Public Health 17, no. 3: 708.

Cambria, Elena, Matthias J. E. Arlt, Sandra Wandel, Olga Krupkova, Wolfgang Hitzl, Fabian S. Passini, Oliver N. Hausmann, Jess G. Snedeker, Stephen J. Ferguson, and Karin Wuertz-Kozak. 2020. "TRPV4 Inhibition and CRISPR-Cas9 Knockout Reduce Inflammation Induced by Hyperphysiological Stretching in Human Annulus Fibrosus Cells" Cells 9, no. 7: 1736.

Rogerio N. Soares, Erin Calaine Inglis, Rojan Khoshreza, Juan M. Murias, Saied Jalal Aboodarda, Rolling massage acutely improves skeletal muscle oxygenation and parameters associated with microvascular reactivity: The first evidence-based study, Microvascular Research, Volume 132, 2020, 104063, ISSN 0026-2862,

2019 and earlier

Passmore SR, Gelley GM, Malone Q, MacNeil BJ. Tactile Perception of Pressure and Volitional Thrust Intensity Modulate Spinal Manipulation Dose Characteristics. J Manipulative Physiol Ther. 2019 Jun;42(5):335-342. doi: 10.1016/j.jmpt.2018.11.017. Epub 2019 Jul 2. PMID: 31272711.

Jiyao Sheng, Shui Liu, Yicun Wang, Ranji Cui, Xuewen Zhang, "The Link between Depression and Chronic Pain: Neural Mechanisms in the Brain", Neural Plasticity, vol. 2017, Article ID 9724371, 10 pages, 2017.

Gregory D. Cramer, Matthew Budavich, Preetam Bora, Kim Ross, A Feasibility Study to Assess Vibration and Sound From Zygapophyseal Joints During Motion Before and After Spinal Manipulation, Journal of Manipulative and Physiological Therapeutics, Volume 40, Issue 3, 2017, Pages 187-200, ISSN 0161-4754,

Yoshida, S. et al. (2017). Dynamic Analysis of Human Knee. In: Korach, C., Tekalur, S., Zavattieri, P. (eds) Mechanics of Biological Systems and Materials, Volume 6. Conference Proceedings of the Society for Experimental Mechanics Series. Springer, Cham.

Hancock, M.J., Maher, C.G., Laslett, M., Hay, E., and Koes, B., "Discussion paper: what happened to the 'bio' in the bio-psycho-social model of low back pain?European Spine Journal 20:2105, 2011. DOI: 10.1007/s00586-011-1886-3.

BOWEN, VAUGHAN; CASSIDY, J. DAVID. Macroscopic and Microscopic Anatomy of the Sacroiliac Joint from Embryonic Life Until the Eighth Decade. Spine 6(6):p 620-628, November 1981.